Van Hoecke, Lien: search on Z-Library

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1

mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice

Van Hoecke, Lien, Verbeke, Rein, De Vlieger, Dorien, Dewitte, Heleen, Roose, Kenny, Van Nevel, Sharon, Krysko, Olga, Bachert, Claus, Schepens, Bert, Lentacker, Ine, Saelens, Xavier

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

File:

PDF, 2.18 MB

2020

2

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

Van Hoecke, Lien, Van Lint, Sandra, Roose, Kenny, Van Parys, Alexander, Vandenabeele, Peter, Grooten, Johan, Tavernier, Jan, De Koker, Stefaan, Saelens, Xavier

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 3.22 MB

english, 2018

3

Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice

Smet, Muriel, Van Hoecke, Lien, De Beuckelaer, Ans, Vander Beken, Seppe, Naessens, Thomas, Vergote, Karl, Willart, Monique, Lambrecht, Bart N., Gustafsson, Jan-Åke, Steffensen, Knut R., Grooten, Johan

Journal:

Immunity, Inflammation and Disease

Year:

2016

Language:

english

File:

PDF, 2.00 MB

english, 2016

4

Intracellular Delivery of mRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation

Raes, Laurens, Stremersch, Stephan, Fraire, Juan C., Brans, Toon, Goetgeluk, Glenn, De Munter, Stijn, Van Hoecke, Lien, Verbeke, Rein, Van Hoeck, Jelter, Xiong, Ranhua, Saelens, Xavier, Vandekerckhove

Journal:

Nano-Micro Letters

Year:

2020

File:

PDF, 1.74 MB

2020

5

Mycobacterium tuberculosis -associated synthetic mycolates differentially exert immune stimulatory adjuvant activity

Smet, Muriel, Pollard, Charlotte, De Beuckelaer, Ans, Van Hoecke, Lien, Beken, Seppe Vander, De Koker, Stefaan, Dulayymi, Juma'a R. Al, Huygen, Kris, Verschoor, Jan, Baird, Mark S., Grooten, Johan

Journal:

European Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 800 KB

english, 2016

6

Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as Vaccine Adjuvant

Van Herck, Simon, Van Hoecke, Lien, Louage, Benoit, Lybaert, Lien, De Coen, Ruben, Kasmi, Sabah, Esser-Kahn, Aaron P, David, Sunil A., Nuhn, Lutz, Schepens, Bert, Saelens, Xavier, De Geest, Bruno G.

Journal:

Bioconjugate Chemistry

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

7

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

Nuhn, Lutz, Van Hoecke, Lien, Deswarte, Kim, Schepens, Bert, Li, Yupeng, Lambrecht, Bart N., De Koker, Stefaan, David, Sunil A., Saelens, Xavier, De Geest, Bruno G.

Journal:

Year:

2018

Language:

english

File:

PDF, 9.24 MB

english, 2018

8

Surfactant protein b (sp-b) enhances the cellular sirna delivery of proteolipid coated nanogels for inhalation therapy

Merckx, Pieterjan, De Backer, Lynn, Van Hoecke, Lien, Guagliardo, Roberta, Echaide, Mercedes, Baatsen, Pieter, Olmeda, Bárbara, Saelens, Xavier, Pérez-Gil, Jésus, De Smedt, Stefaan C., Raemdonck, Koen

Journal:

Acta Biomaterialia

Year:

2018

Language:

english

File:

PDF, 2.14 MB

english, 2018

9

How mRNA therapeutics are entering the monoclonal antibody field

Van Hoecke, Lien, Roose, Kenny

Journal:

Journal of Translational Medicine

Year:

2019

Language:

english

File:

PDF, 2.05 MB

english, 2019

10

Chemical-controlled Activation of Antiviral Myxovirus Resistance Protein 1

Verhelst, Judith, Van Hoecke, Lien, Spitaels, Jan, De Vlieger, Dorien, Kolpe, Annasaheb, Saelens, Xavier

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 3.77 MB

english, 2017

11

Clinical burden of Hepatitis E virus infection in a tertiary care center in Flanders, Belgium

Cattoir, Lien, Van Hoecke, Frederik, Van Maerken, Tom, Nys, Eveline, Ryckaert, Inge, De Boulle, Matthias, Geerts, Anja, Verhelst, Xavier, Colle, Isabelle, Hutse, Veronik, Suin, Vanessa, Wautier, Magal

Journal:

Journal of Clinical Virology

Year:

2018

Language:

english

File:

PDF, 306 KB

english, 2018

12

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

Joe, Patrick Tjok, Christopoulou, Ioanna, van Hoecke, Lien, Schepens, Bert, Ysenbaert, Tine, Heirman, Carlo, Thielemans, Kris, Saelens, Xavier, Aerts, Joeri L.

Journal:

Journal of Translational Medicine

Year:

2019

Language:

english

File:

PDF, 907 KB

english, 2019

13

GM-CSF treatment prevents respiratory syncytial virus–induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation

Naessens, Thomas, Schepens, Bert, Smet, Muriel, Pollard, Charlotte, Van Hoecke, Lien, De Beuckelaer, Ans, Willart, Monique, Lambrecht, Bart, De Koker, Stefaan, Saelens, Xavier, Grooten, Johan

Journal:

Journal of Allergy and Clinical Immunology

Year:

2015

Language:

english

File:

PDF, 2.33 MB

english, 2015

14

Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses

De Beuckelaer, Ans, Pollard, Charlotte, Van Lint, Sandra, Roose, Kenny, Van Hoecke, Lien, Naessens, Thomas, Udhayakumar, Vimal Kumar, Smet, Muriel, Sanders, Niek, Lienenklaus, Stefan, Saelens, Xavier,

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 1.37 MB

english, 2016

15

Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice

Van Hoecke, Lien, Riederer, Stephanie, Saelens, Xavier, Sutter, Gerd, Rojas, Juan JosÃ©

Journal:

Year:

2020

File:

PDF, 2.49 MB

2020

16

Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells

Van Hoecke, Lien, Raes, Laurens, Stremersch, Stephan, Brans, Toon, Fraire, Juan C., Roelandt, Ria, Declercq, Wim, Vandenabeele, Peter, Raemdonck, Koen, Braeckmans, Kevin, Saelens, Xavier

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 2.30 MB

english, 2019

17

The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration

Van Hoecke, Lien, Roose, Kenny, Ballegeer, Marlies, Zhong, Zifu, Sanders, Niek N., De Koker, Stefaan, Saelens, Xavier, Van Lint, Sandra

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

File:

PDF, 1.53 MB

2020

18

Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines

Lambricht, Laure, Vanvarenberg, Kevin, De Beuckelaer, Ans, Van Hoecke, Lien, Grooten, Johan, Ucakar, Bernard, Lipnik, Pascale, Sanders, Niek N, Lienenklaus, Stefan, Préat, Véronique, Vandermeulen, Gaë

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 8.40 MB

english, 2016

19

Specific targeting of IL-1Î² activity to CD8+ T cells allows for safe use as a vaccine adjuvant

Van Den Eeckhout, Bram, Van Hoecke, Lien, Burg, Elianne, Van Lint, Sandra, Peelman, Frank, Kley, Niko, UzÃ©, Gilles, Saelens, Xavier, Tavernier, Jan, Gerlo, Sarah

Journal:

Year:

2020

File:

PDF, 4.07 MB

2020

20

Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide

Udhayakumar, Vimal K., De Beuckelaer, Ans, McCaffrey, Joanne, McCrudden, Cian M., Kirschman, Jonathan L., Vanover, Daryll, Van Hoecke, Lien, Roose, Kenny, Deswarte, Kim, De Geest, Bruno G., Lienenklau

Journal:

Advanced Healthcare Materials

Year:

2017

Language:

english

File:

PDF, 3.02 MB

english, 2017

21

Hepatitis E virus serology and PCR: does the methodology matter?

Cattoir, Lien, Van Hoecke, Frederik, Van Maerken, Tom, Nys, Eveline, Ryckaert, Inge, De Boulle, Matthias, Geerts, Anja, Verhelst, Xavier, Colle, Isabelle, Hutse, Veronik, Suin, Vanessa, Wautier, Magal

Journal:

Archives of Virology

Year:

2017

Language:

english

File:

PDF, 607 KB

english, 2017

22

Bronchoalveolar Lavage of Murine Lungs to Analyze Inflammatory Cell Infiltration

Van Hoecke, Lien, Job, Emma Richelle, Saelens, Xavier, Roose, Kenny

Journal:

Journal of Visualized Experiments

Year:

2017

Language:

english

File:

PDF, 360 KB

english, 2017

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